Document Detail


Multiple chromosome aberrations in an infant with acute monoblastic leukemia.
MedLine Citation:
PMID:  3180019     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A male infant was diagnosed at age 16 months with acute monoblastic leukemia. At diagnosis, studies of bone marrow revealed multiple chromosome aberrations: 48,XY,+8,+19,t(4;11). Chromosome studies have been repeated at remission and relapse over the course of his disease. To our knowledge, this combination of chromosome abnormalities has not been previously reported.
Authors:
L E McMorrow; B H Greenbaum; S F Travis; M H Donaldson; M K McCormack
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  35     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1988 Oct 
Date Detail:
Created Date:  1988-12-06     Completed Date:  1988-12-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  167-70     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, UMDNJ-School of Osteopathic Medicine, Camden 08103.
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MeSH Terms
Descriptor/Qualifier:
Bone Marrow / ultrastructure
Chromosome Aberrations*
Humans
Infant
Karyotyping
Leukemia, Monocytic, Acute / genetics*
Male

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