Document Detail


Multiple chondromatous hamartomas of the lung: a case report and review of the literature with special reference to Carney syndrome.
MedLine Citation:
PMID:  10375102     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Multiple chondromatous hamartomas of the lung, which are very rare, are a feature of Carney syndrome. The relation between the two entities is not clear. METHODS: A patient with multiple chondromatous hamartomas of the lung is described in this article. The literature was reviewed with special reference to the relation between multiple chondromatous hamartomas of the lung and Carney syndrome as well as the triad of gastric epithelioid leiomyosarcoma, functioning extra-adrenal paraganglioma, and pulmonary chondroma. RESULTS: A total of 15 cases of multiple chondromatous hamartomas of the lung have been published worldwide. Two cases exhibited two other features of Carney syndrome, namely, gastric leiomyogenic neoplasms and extra-adrenal paragangliomas, and three other cases demonstrated only gastric leiomyomatous neoplasms. These five patients were all young females. CONCLUSIONS: Some patients with multiple chondromatous hamartomas of the lung have a history of Carney syndrome. Patients with multiple chondromatous hamartomas require further examination of other sites, particularly the stomach and nervous system.
Authors:
T Kiryu; S Kawaguchi; E Matsui; H Hoshi; M Kokubo; K Shimokawa
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Cancer     Volume:  85     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-06-30     Completed Date:  1999-06-30     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2557-61     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Gifu University School of Medicine, Gifu City, Japan.
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MeSH Terms
Descriptor/Qualifier:
Chondromatosis / diagnosis,  pathology*
Hamartoma Syndrome, Multiple / diagnosis,  pathology*
Humans
Lung / pathology
Lung Neoplasms / diagnosis,  pathology*
Male
Middle Aged
Comments/Corrections
Comment In:
Cancer. 2000 Feb 15;88(4):964-5   [PMID:  10679667 ]

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