Document Detail


Multiple attempts at embryo transfer: effect on pregnancy outcome in an in vitro fertilization and embryo transfer program.
MedLine Citation:
PMID:  8499677     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: This study derives from the observation that a correlation exists between failed first attempts (FFA) at embryo transfer caused by one or more embryos remaining in the catheter and reduced pregnancy rates (20.3 vs 3.0%). The aim of this study was to examine the relationship between failed first attempts at transfer and contamination of the transfer set; the related aspects of cervix dilatation and late embryo transfer were also investigated. RESULTS: The following observations were made. Retention of embryos in the transfer sets significantly reduced the pregnancy rate (P = 0.015); catheters contaminated with blood and cervical mucus indirectly contributed to this effect by increasing the incidence of failed first transfer attempts. Even though cervical dilatations, if indicated by uterus sounding, were done 2 days before embryo transfer, no pregnancies were effected in these 18 cases (P = 0.0001). Late transfers of embryos, due to delayed fertilization or slow cleavage rates, yielded a pregnancy rate of 10.5%. CONCLUSION: The approach of immediately retransferring retained embryos does not solve the problem of reduced pregnancy rates in FFA cases. It is suggested that ET should be repeated 1 day later in FFA cases in an attempt to improve pregnancy rates.
Authors:
D S Visser; F L Fourie; H F Kruger
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  10     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-06-29     Completed Date:  1993-06-29     Revised Date:  2008-03-18    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  37-43     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, University of Pretoria, RSA.
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MeSH Terms
Descriptor/Qualifier:
Blood
Catheterization
Cervix Mucus
Cervix Uteri
Dilatation
Embryo Transfer / methods*
Female
Fertilization in Vitro*
Humans
Incidence
Pregnancy
Pregnancy Outcome
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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