Document Detail


Multiple risk behaviors among youth living with human immunodeficiency virus in five U.S. cities.
MedLine Citation:
PMID:  20123252     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To describe multiple risk behaviors (substance use, sexual risk, and medication adherence) in a multi-site sample of youth living with human immunodeficiency virus (HIV) in five U.S. cites.
METHODS: Youth (N=352) were recruited from four Adolescent Trials Network (ATN) sites (Philadelphia, Fort Lauderdale, Baltimore, and Los Angeles) and one non-ATN site in Detroit and screened for multiple problem behaviors for an intervention study. A substance abuse problem was determined with the CRAFFT, a six-item adolescent screener. Single items were used to screen for current sexual risk and for an HIV medication adherence problem. Of the youth, 239 (68%) had at least one of the three risk behavior problems based on the screener. A total of 186 (52.8%) completed longer, in-depth questionnaires for each problem behavior.
RESULTS: Of the 352 youth screened, 60% had problem level substance use and 42% had a sexual risk problem. Of the 165 (47%) who were prescribed medications, 91 (55%) reported an adherence problem. A total of 112 (32%) reported no problem behavior, 123 (35%) reported 1 problem behavior, 95 (27%) reported 2 problem behaviors, and 20 (6%) reported 3 problem behaviors. Males were more likely to have a substance use problem. Younger youth living with HIV and those perinatally infected were more likely to have an adherence problem. Among the 186 (52.8%) completing longer measures, those with a substance abuse problem had higher substance use on a timeline follow-back procedure than those without. Participants who screened positive for a sexual risk problem reported more unprotected sex on an in-depth interview than those without. Those who screened positive for an adherence problem had higher viral loads than those without an adherence problem.
CONCLUSIONS: Results suggest high rates of problem behaviors among youth living with HIV, particularly in older youth. Younger and perinatally infected youth may require specialized adherence interventions. Associations between the screener and more in-depth assessment measures suggest potential clinical utility of screening youth for high-risk behaviors.
Authors:
Mary R Tanney; Sylvie Naar-King; Debra A Murphy; Jeffrey T Parsons; Heather Janisse;
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2009-08-18
Journal Detail:
Title:  The Journal of adolescent health : official publication of the Society for Adolescent Medicine     Volume:  46     ISSN:  1879-1972     ISO Abbreviation:  J Adolesc Health     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-03     Completed Date:  2010-05-10     Revised Date:  2011-07-19    
Medline Journal Info:
Nlm Unique ID:  9102136     Medline TA:  J Adolesc Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11-6     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Society for Adolescent Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA. Tanney@email.chop.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Female
HIV Infections / drug therapy
HIV Long-Term Survivors*
Humans
Male
Patient Compliance
Questionnaires
Risk-Taking*
Substance-Related Disorders
United States
Unsafe Sex
Urban Population*
Young Adult
Grant Support
ID/Acronym/Agency:
U01 HD040481-08/HD/NICHD NIH HHS; U01 HD040481-09/HD/NICHD NIH HHS; U01-HD040474/HD/NICHD NIH HHS; U01-HD040533/HD/NICHD NIH HHS
Investigator
Investigator/Affiliation:
Ana Puga / ; Esmine Leonard / ; Zulma Eysallenne / ; Marvin Belzer / ; Cathy Salata / ; Diane Tucker / ; Ligia Peralta / ; Leonel Flores / ; Esther Collinetti / ; Bret Rudy / ; Mary Tanney / ; Naini Seth / ; Kelly Lannutti / ; Andrea Kovacs / ; K Wright / ; P Lam / ; V Conners /
Comments/Corrections

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