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Multiple, Recurrent, Refractory Vascular Malformations as the Primary Presenting Feature of a PTEN Mutation.
MedLine Citation:
PMID:  21793891     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Complete history and physical examinations are very important in patients with a vascular anomaly. This brief report highlights the case of a five-year-old male who presented with recurrent arteriovenous malformations of the hand and forearm. The patient also demonstrated additional clinical and diagnostic imaging features consistent with a PTEN Hamartoma-Tumor syndrome. The prompt identification of individuals with this condition is important, given the more locally aggressive nature to the malformations and the increased potential for future malignant disease. The etiology and clinical features associated with PTEN Hamartoma-Tumor syndromes are reviewed in this case.
Authors:
Safa E Sharabi; John C Koshy; Larry H Hollier
Publication Detail:
Type:  Journal Article     Date:  2010-12-02
Journal Detail:
Title:  Pediatric dermatology     Volume:  28     ISSN:  1525-1470     ISO Abbreviation:  Pediatr Dermatol     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  466-7     Citation Subset:  IM    
Copyright Information:
© 2011 Wiley Periodicals, Inc.
Affiliation:
Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas.
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