| Multiple equilibrium states in a micro-vascular network. | |
| | |
MedLine Citation:
|
PMID: 20627109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We use a simple model of micro-vascular blood flow to explore conditions that give rise to multiple equilibrium states in a three-node micro-vascular network. The model accounts for two primary rheological effects: the Fåhraeus-Lindqvist effect, which describes the apparent viscosity of blood in a vessel, and the plasma skimming effect, which governs the separation of red blood cells at diverging nodes. We show that multiple equilibrium states are possible, and we use our analytical and computational tools to design an experiment for validation. |
| | |
Authors:
|
David Gardner; Yiyang Li; Benjamin Small; John B Geddes; Russell T Carr |
Related Documents
:
|
9163069 - Decreased erythrocyte deformability in glycogen storage disease. 15258369 - Evaluation of the hemorheological and neurosonographic relationship in patients with ce... 9508279 - Nmr studies of intra- and extracellular red blood cell lithium by transverse relaxation... 8908629 - Observations on isovolemic hemodilution in acute ischemic stroke. 58309 - Abnormal blood viscosity in raynaud's phenomenon. 9699039 - Impact of pancreas and kidney transplantation on determinants of blood and plasma visco... 16766479 - Analysis of algorithms predicting blood:air and tissue:blood partition coefficients fro... 3279689 - Resistance index, blood flow velocity, and resistance-area product in the cerebral arte... 7102799 - Effect of tropicamide on ocular blood flow in the rabbit. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-07-11 |
Journal Detail:
|
Title: Mathematical biosciences Volume: 227 ISSN: 1879-3134 ISO Abbreviation: Math Biosci Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-08-31 Completed Date: 2011-02-02 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0103146 Medline TA: Math Biosci Country: United States |
Other Details:
|
Languages: eng Pagination: 117-24 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Franklin W. Olin College of Engineering, Needham, MA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Algorithms Biomechanics Blood Pressure / physiology Blood Viscosity / physiology Cell Movement / physiology Computer Simulation Erythrocytes / cytology Hematocrit Hemorheology / physiology* Microvessels / anatomy & histology, physiology* Models, Biological* Nonlinear Dynamics Regional Blood Flow / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Positive interactions and the emergence of community structure in metacommunities.
Next Document: Inferring ancestral sequences in taxon-rich phylogenies.