| Multiple Cutaneous Plexiform Schwannomas as Initial Presentation of Neurofibromatosis 2 in a 9-Year-Old. | |
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MedLine Citation:
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PMID: 21906157 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Neurofibromatosis 2 (NF2) is an autosomal-dominant disease caused by genetic mutations of the NF2 gene on chromosome 22. Patients are often diagnosed according to the presence of bilateral vestibular schwannomas and other tumors in the brain and spinal cord. In children, NF2 can present early with ocular findings and cutaneous tumors. We report here a 9-year-old girl who presented with multiple pigmented, slightly tender plaques on her scalp, face, and back that were revealed by histopathology to be plexiform schwannomas. We suspected NF2 and sent the patient's blood for genetic testing, which confirmed our diagnosis. |
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Authors:
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Tien V Nguyen; Mark R Matthews; Fernando F Barrera; John C Browning |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-9 |
Journal Detail:
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Title: Pediatric dermatology Volume: - ISSN: 1525-1470 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8406799 Medline TA: Pediatr Dermatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Wiley Periodicals, Inc. |
Affiliation:
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Division of Dermatology and Cutaneous Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas Pathology Reference Laboratory, San Antonio, Texas Division of Dermatology, Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas. |
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