Document Detail


Multiple cranial nerve enhancement on MRI in primary Sjögren's syndrome.
MedLine Citation:
PMID:  20453408     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 77-year-old man showed bilateral abducens palsies and multiple cranial nerve enhancement on magnetic resonance images (MRI) and aseptic meningitis. He had xerophthalmia and xerostomia. Serum anti-SS-A and anti-SS-B antibodies were present. He had Sjögren's syndrome (SjS) and corticosteroid therapy ameliorated the symptoms. The cranial nerve enhancement and the cerebrospinal fluid findings were normalized. In patients with SjS, there have not been any reports of multiple areas of cranial nerve enhancement on MRI. We propose that in this case the aseptic meningitis and subsequent lymphocytic infiltration to the cranial nerves contributed to the multiple cranial neuropathy and multiple cranial nerve enhancement on MRI.
Authors:
Kenji Sakai; Tsuyoshi Hamaguchi; Masahito Yamada
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-04-30
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  49     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-10     Completed Date:  2010-08-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  857-9     Citation Subset:  IM    
Affiliation:
Department of Neurology, Noto General Hospital, Nanao. ksakai@med.kanazawa-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Abducens Nerve Diseases / diagnosis,  drug therapy,  etiology
Aged
Cranial Nerve Diseases / diagnosis*,  drug therapy,  etiology
Follow-Up Studies
Gadolinium / diagnostic use
Humans
Magnetic Resonance Imaging / methods*
Male
Meningitis, Aseptic / diagnosis*,  etiology,  therapy
Methylprednisolone / therapeutic use
Paralysis / diagnosis,  drug therapy,  etiology
Risk Assessment
Severity of Illness Index
Sjogren's Syndrome / complications*,  diagnosis
Treatment Outcome
Chemical
Reg. No./Substance:
7440-54-2/Gadolinium; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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