Document Detail

Multiphoton microscopic imaging of normal human rectum tissue.
MedLine Citation:
PMID:  20718013     Owner:  NLM     Status:  In-Data-Review    
In this paper, multiphoton microscopy (MPM), based on two-photon excited fluorescence and second harmonic generation signals, was used to image microstructures of human rectal mucosa and submucosa. The morphology and distribution of the main components in mucosa layer, goblet cells, intestinal glands, and a little collagen fibers have been clearly monitored, and the content and distribution of collagen, elastic fibers, and blood vessels in submucosa layer have also been distinctly obtained. The variation of these components is very relevant to the pathology in gastrointestinal system, especially early rectal cancer. Our results indicate that the MPM technique has the potential application in vivo in the clinical diagnosis and monitoring of early rectal cancer. SCANNING 32: 347-350, 2010. © 2010 Wiley Periodicals, Inc.
Nenrong Liu; Gang Chen; Jianxin Chen; Jun Yan; Shuangmu Zhuo; Liqin Zheng; Xingshan Jiang
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Publication Detail:
Type:  Journal Article     Date:  2010-08-17
Journal Detail:
Title:  Scanning     Volume:  32     ISSN:  1932-8745     ISO Abbreviation:  Scanning     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2011-01-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903371     Medline TA:  Scanning     Country:  United States    
Other Details:
Languages:  eng     Pagination:  347-50     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Wiley Periodicals, Inc.
Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, China.
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