Document Detail


Multiorgan damage in acute oral carbamates poisonings.
MedLine Citation:
PMID:  9478086     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of the study was to evaluate the frequency and the kind of multiorgan damage in acute oral carbamates poisonings. Under analysis there were 36 carbamates orally poisoned patients treated at the Department of Clinical Toxicology in the years 1987-1997. Patients with the liver or biliary tract diseases, chronic circulatory insufficiency symptoms, HBs antigen carriers, who suffered head traumas, CNS illness and heavy drinkers were excluded from the study. The organs damage was noted in 91.7% of the poisoned patients. The respiratory system followed by the CNS and the liver were mostly affected by carbamates toxicity. The frequency of pathological changes in the kidney and circulatory system was relatively lower. Only in a few persons peripheral nervous system injuries were noted. In 15% of the examined group the injuries of one organ only was stated. In 48.5% of the patients simultaneous injury of two and three organs or systems were noted. 36.3% of the patients suffered from multiorgan (four or more) damage. In all the severely poisoned patients (III degree) the organs damage was noted. In 53% of them the simultaneous damage of four or more organs/systems was noted. In the group of patients stated as moderately poisoned on admission to the clinic, the multiorgan damage (2-3 organs/systems) was found in 77% of the patients. The lowest number of organ damage was observed in the group of slightly poisoned patients.
Authors:
L Winnik; D Pach; T Gawlikowski; D Targosz; P Hydzik
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Przegla̧d lekarski     Volume:  54     ISSN:  0033-2240     ISO Abbreviation:  Prz. Lek.     Publication Date:  1997  
Date Detail:
Created Date:  1998-04-16     Completed Date:  1998-04-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  19840720R     Medline TA:  Przegl Lek     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  684-8     Citation Subset:  IM    
Affiliation:
Department of Clinical Toxicology, Collegium Medicum, Jagiellonian University in Kraków.
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MeSH Terms
Descriptor/Qualifier:
Acetylcholinesterase / blood
Adolescent
Adult
Aged
Carbamates / analysis,  poisoning*
Chi-Square Distribution
Erythrocytes / enzymology
Female
Humans
Incidence
Male
Middle Aged
Multiple Organ Failure / chemically induced*,  diagnosis,  epidemiology
Poisoning / classification
Chemical
Reg. No./Substance:
0/Carbamates; EC 3.1.1.7/Acetylcholinesterase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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