Document Detail

Multimorbidity in Heart Failure: A Community Perspective.
MedLine Citation:
PMID:  25220613     Owner:  NLM     Status:  Publisher    
BACKGROUND: Comorbidities are a major concern in heart failure, leading to adverse outcomes, increased healthcare utilization, and excess mortality. Nevertheless, the epidemiology of comorbid conditions and differences in their occurrence by type of heart failure and sex are not well documented.
METHODS: The prevalence of 16 chronic conditions defined by the US Department of Health and Human Services was obtained among 1,382 patients from Olmsted County, Minnesota diagnosed with first-ever heart failure between 2000 and 2010. Heat maps displayed the pairwise prevalences of the comorbidities and the observed-to-expected ratios for occurrence of morbidity pairs by type of heart failure (preserved or reduced ejection fraction) and sex.
RESULTS: Most heart failure patients had 2 or more additional chronic conditions (86%); the most prevalent were hypertension, hyperlipidemia, and arrhythmias. The co-occurrence of other cardiovascular diseases was common, with higher prevalences of co-occurring cardiovascular diseases in men compared to women. Patients with preserved ejection fraction had 1 additional condition compared to those with reduced ejection fraction (mean 4.5 vs. 3.7). The patterns of co-occurring conditions were similar between preserved and reduced ejection fraction; however, differences in the ratios of observed-to-expected co-occurrence were apparent by type of heart failure and sex. In addition, some psychological and neurological conditions co-occurred more frequently than expected.
CONCLUSION: Multimorbidity is common in heart failure, and differences in co-occurrence of conditions exist by type of heart failure and sex, highlighting the need for a better understanding of the clinical consequences of multiple chronic conditions in heart failure patients.
Alanna M Chamberlain; Jennifer L St Sauver; Yariv Gerber; Sheila M Manemann; Cynthia M Boyd; Shannon M Dunlay; Walter A Rocca; Lila J Finney Rutten; Ruoxiang Jiang; Susan A Weston; Véronique L Roger
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-11
Journal Detail:
Title:  The American journal of medicine     Volume:  -     ISSN:  1555-7162     ISO Abbreviation:  Am. J. Med.     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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