| Multimodal approach in the surgical treatment of refractory epilepsy associated with tuberous sclerosis complex: A series of three cases. | |
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MedLine Citation:
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PMID: 22019663 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We describe the surgical treatment of tuberous sclerosis complex (TSC)-related refractory epilepsy in three patients. All three had multiple daily seizures, and each had more than three cortical tubers. High-resolution magnetic resonance imaging, ictal and interictal scalp electroencephalogram (EEG), positron emission tomography, magnetoencephalography as well as acute and intracranial video-EEG were used to identify the epileptogenic tubers. After localization, five cortical tubers (two in the right temporal lobe in patient 1; one each in the left frontal and temporal lobes in patient 2; and one in the right frontal lobe in patient 3) were resected. At minimum follow-up of 13 months (range, 13-35 months), patient 3 had seizure remission; patient 2 had only rare seizures; while patient 1 had 60% reduction in seizure frequency. Successful epilepsy surgery is possible in patients of TSC with multiple tubers using the multimodal approach. |
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Authors:
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Qiang Li; Chao You; Yuan Fang; Jianguo Xu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurology India Volume: 59 ISSN: 0028-3886 ISO Abbreviation: Neurol India Publication Date: 2011 Sep-Oct |
Date Detail:
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Created Date: 2011-10-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0042005 Medline TA: Neurol India Country: India |
Other Details:
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Languages: eng Pagination: 748-52 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, China. |
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