Document Detail


Multimodal MRI assessment of damage and plasticity caused by status epilepticus in the rat brain.
MedLine Citation:
PMID:  21967365     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Status epilepticus or other brain-damaging insults launch a cascade of events that may lead to the development of epilepsy. MRI techniques available today, including T(2) - and T(1) -weighted imaging, functional MRI, manganese enhanced MRI (MEMRI), arterial spin labeling (ASL), diffusion tensor imaging (DTI), and phase imaging, can detect not only damage caused by status epilepticus but also plastic changes in the brain that occur in response to damage. Optimal balance between damage and recovery processes is a key for planning possible treatments, and noninvasive imaging has the potential to greatly facilitate this process and to make personalized treatment plans possible.
Authors:
Olli Gröhn; Alejandra Sierra; Riikka Immonen; Teemu Laitinen; Kimmo Lehtimäki; Antti Airaksinen; Nick Hayward; Jaak Nairismagi; Lauri Lehto; Asla Pitkänen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Epilepsia     Volume:  52 Suppl 8     ISSN:  1528-1167     ISO Abbreviation:  Epilepsia     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  57-60     Citation Subset:  IM    
Copyright Information:
Wiley Periodicals, Inc. © 2011 International League Against Epilepsy.
Affiliation:
Biomedical NMR Research Group Epilepsy Research Laboratory, Department of Neurobiology, A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
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