Document Detail


Multilocus and single locus minisatellite analysis in population biological studies.
MedLine Citation:
PMID:  1831157     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this review we describe the situations in which minisatellite analysis is of value to studies of population and evolutionary biology. Evolutionary and population biologists need to be able to quantify genetic relationships among individual organisms at many different levels, from close familial relationships to evolutionarily distant phylogenetic ones. The use of minisatellite markers is put into this context and compared with the other molecular biological techniques. Examples of the use of multilocus minisatellite analysis in population biology are described. The limitations of multilocus fingerprinting are presented, together with the potential advantages of locus-specific probes. The use of locus-specific probes in population biology is now often feasible due to the recent development of a cloning system which allows their efficient isolation. The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
Authors:
T Burke; O Hanotte; M W Bruford; E Cairns
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  EXS     Volume:  58     ISSN:  1023-294X     ISO Abbreviation:  EXS     Publication Date:  1991  
Date Detail:
Created Date:  1991-09-19     Completed Date:  1991-09-19     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9204529     Medline TA:  EXS     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  154-68     Citation Subset:  IM    
Affiliation:
Department of Zoology, University of Leicester, Great Britain.
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MeSH Terms
Descriptor/Qualifier:
Animals
DNA Fingerprinting
DNA, Satellite*
Evolution
Genetics, Population*
Humans
Polymorphism, Genetic*
Chemical
Reg. No./Substance:
0/DNA, Satellite

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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