Document Detail


Multilocus enzyme electrophoresis for identification and typing of Treponema hyodysenteriae and related spirochaetes.
MedLine Citation:
PMID:  2336787     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An assessment was made of multilocus enzyme electrophoresis as a means of identifying and typing spirochaetes isolated from pigs. Using five enzyme systems, 36 isolates from Australia, the U.K. and the U.S.A. were divided into 12 electrophoretic types or multilocus genotypes, comprising four major, genetically distinct groups. All 26 isolates of Treponema hyodysenteriae fell into one group, members of which showed relatively little genetic diversity. Ten isolates of non-pathogenic spirochaetes fell into three genetically different groups. Although the technique was capable of typing organisms within the groups, it was not always as discriminatory as DNA-restriction endonuclease analysis. Examination of additional enzyme loci should increase the sensitivity of the method for typing and for overall assessment of genetic relationships between spirochaetes.
Authors:
A J Lymbery; D J Hampson; R M Hopkins; B Combs; J R Mhoma
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Veterinary microbiology     Volume:  22     ISSN:  0378-1135     ISO Abbreviation:  Vet. Microbiol.     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-06-12     Completed Date:  1990-06-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7705469     Medline TA:  Vet Microbiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  89-99     Citation Subset:  IM    
Affiliation:
School of Veterinary Studies, Murdoch University, W.A., Australia.
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MeSH Terms
Descriptor/Qualifier:
Alleles*
Animals
Enzymes / analysis*,  genetics
Genetic Variation
Treponema / classification*,  enzymology,  genetics
Chemical
Reg. No./Substance:
0/Enzymes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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