| Multilobated B-cell lymphoma, a variant of centroblastic lymphoma. Report of four cases. | |
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MedLine Citation:
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PMID: 3089898 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Four cases of multilobated B-cell lymphoma, one follicular and three diffuse, are described. Many of the lymphoma cells show marked lobulation of the nuclei, and possess multiple prominent nucleoli. There are admixed classical centrocytes, classical centroblasts, and cells with morphology intermediate between classical centroblasts and multilobated cells. Multilobated cells are also observed in small numbers in germinal centres of lymph nodes showing reactive follicular hyperplasia. We believe that the multilobated B-cell may represent one form of centroblast during transition between the centroblastic and centrocytic stages. Multilobated B-cell lymphoma may be its neoplastic counterpart in which the nuclear lobulation is further exaggerated. |
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Authors:
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J K Chan; C S Ng; S Tung |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Histopathology Volume: 10 ISSN: 0309-0167 ISO Abbreviation: Histopathology Publication Date: 1986 Jun |
Date Detail:
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Created Date: 1986-09-17 Completed Date: 1986-09-17 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7704136 Medline TA: Histopathology Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 601-12 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Antigens, Differentiation, T-Lymphocyte Antigens, Surface / analysis B-Lymphocytes / pathology* Cell Nucleus / pathology Cell Transformation, Neoplastic / pathology* Cytoplasm / immunology Female Humans Lymph Nodes / pathology Lymphoma, Non-Hodgkin / analysis, classification, pathology* Male Middle Aged Receptors, Antigen, B-Cell / analysis |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Differentiation, T-Lymphocyte; 0/Antigens, Surface; 0/Receptors, Antigen, B-Cell |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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