Document Detail


Multifunctional Fe3O4/TaOx Core/Shell Nanoparticles for Simultaneous Magnetic Resonance Imaging and X-ray Computed Tomography.
MedLine Citation:
PMID:  22676237     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Multimodal imaging is highly desirable for accurate diagnosis because it can provide complementary in-formation of each imaging modality. In this study, multifunctional Fe3O4/TaOx core/shell nanoparticles were synthesized using a sol-gel reaction of tantalum (V) ethoxide in a microemulsion containing Fe3O4 nanoparticles. The resulting nanoparticles were biocompatible and exhibited prolonged circulation time. When the nanoparticles were intravenously injected, the tumor-associated vessel and the microenvironment of the tumor were observed with computed tomography (CT) and magnetic resonance imaging (MRI), respectively.
Authors:
Nohyun Lee; Hye Rim Cho; Myoung Hwan Oh; Soo Hong Lee; Kangmin Kim; Byung Hyo Kim; Kwangsoo Shin; Tae-Young Ahn; Jin Woo Choi; Young-Woon Kim; Seung Hong Choi; Taeghwan Hyeon
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-7
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  -     ISSN:  1520-5126     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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