| Multifocal visual evoked potential latency analysis: predicting progression to multiple sclerosis. | |
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MedLine Citation:
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PMID: 16769865 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To monitor the difference in conversion rates to multiple sclerosis (MS) in 46 patients with optic neuritis between patients with multifocal visual evoked potential latency delay and those with normal latency. DESIGN: Prospective case series. SETTING: Metropolitan neuro-ophthalmology clinic. PARTICIPANTS: Forty-six patients with optic neuritis who did not have a diagnosis of MS on enrollment in the study. MAIN OUTCOME MEASURES: Conversion to MS according to the McDonald criteria. RESULTS: Analysis revealed that only 22 subjects had multifocal visual evoked potential latency delay. Over 1 year, 36.4% of patients with optic neuritis with latency delays progressed clinically to MS compared with 0% of those with normal latencies (P = .03, chi2). CONCLUSION: This may indicate that multifocal visual evoked potential latency delay can assist in predicting progression to future MS. |
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Authors:
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Clare Fraser; Alexander Klistorner; Stuart Graham; Raymond Garrick; Francis Billson; John Grigg |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Archives of neurology Volume: 63 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-06-13 Completed Date: 2006-07-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 847-50 Citation Subset: AIM; IM |
Affiliation:
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Save Sight Institute, Sydney, NSW, Australia. manuscript@clarefraser.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Evoked Potentials, Visual / physiology* Female Humans Male Multiple Sclerosis / complications, physiopathology* Optic Neuritis / complications, physiopathology* Pattern Recognition, Visual / physiology Photic Stimulation / methods Prospective Studies Reaction Time / physiology* |
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