| Multifocal malignant melanoma arising in vesicovaginal melanosis. | |
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MedLine Citation:
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PMID: 1929794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An 80-year-old white woman developed vulvar melanosis and malignant melanoma of the labia majora and clitoris and underwent a simple vulvectomy. She subsequently developed melanosis of the urinary bladder and presented 3 years later with multifocal malignant melanoma involving the vagina, urethra, and urinary bladder in a background of extensive melanosis with variable degrees of atypia. She underwent radical surgery but died 18 months later with liver metastases and liver failure. Malignant melanoma is uncommon in the vulva and vagina and is rare in the urinary bladder. This case illustrates the previously described association between melanosis and malignant melanoma. The unusual features are the widespread distribution of the melanosis (vagina and bladder) and the subsequent development of multifocal malignant melanoma. |
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Authors:
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S W Kerley; M L Blute; G L Keeney |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Archives of pathology & laboratory medicine Volume: 115 ISSN: 0003-9985 ISO Abbreviation: Arch. Pathol. Lab. Med. Publication Date: 1991 Sep |
Date Detail:
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Created Date: 1991-10-30 Completed Date: 1991-10-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7607091 Medline TA: Arch Pathol Lab Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 950-2 Citation Subset: AIM; IM |
Affiliation:
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Department of Pathology, Mayo Clinic, Rochester, MN 55905. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Female Humans Melanoma / complications*, pathology Melanosis / complications*, pathology Urinary Bladder Diseases / complications*, pathology Urinary Bladder Neoplasms / complications*, pathology Vaginal Diseases / complications*, pathology Vaginal Neoplasms / complications*, pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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