Document Detail


Multifocal fibrosclerosis: retroperitoneal fibrosis associated with a suprasellar tumor and pachymeningitis.
MedLine Citation:
PMID:  14606716     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 42 year-old man with lumbago and fever had hydronephrosis due to a mass surrounding the abdominal aorta, associated with pachymeningitis and a suprasellar tumor. He was given a diagnosis of multifocal fibrosclerosis, involving both retroperitoneal and intracranial fibrosis. He responded to treatment with corticosteroid and cyclophosphamide. The intracranial lesions seemed to be rare, but important manifestations of the systemic disease, and were clearly visualized by magnetic resonance imaging. The phenotype of the infiltrated lymphocytes was CD4+, supporting the hypothesis that autoimmunity was involved pathogenetically. We propose a comprehensive category termed "inflammatory fibrotic disease" including both systemic and localized diseases.
Authors:
Wataru Fukuda; Mizuho Kimura; Teruaki Akaogi; Masami Sako; Kaiyo Ohiwa; Yasumasa Yamamoto; Genichi Kato; Hideo Hayashi; Toshikazu Yoshikawa
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  42     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-11-10     Completed Date:  2004-03-12     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1006-10     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Kyoto Second Red-Cross Hospital, Kyoto.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Neoplasms / complications*,  diagnosis,  therapy
Humans
Male
Meningitis / complications*,  diagnosis,  therapy
Retroperitoneal Fibrosis / complications*,  diagnosis,  therapy

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