Document Detail


Multifetal pregnancy reduction in Sweden. Utilization rate and pregnancy outcome (1986-1992)
MedLine Citation:
PMID:  8009972     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
All departments of Obstetrics and Gynecology, as well as all private clinics in Sweden offering assisted conception, were surveyed by means of a questionnaire to determine the utilization rate and outcome of multifetal pregnancy reduction (MFR) for the period 1 January 1986 to 30 June 1992. The response rae was 100%. Multifetal reduction was performed in 26 women, giving an average utilization rate of 1/7 multiple births of three or more for the entire period. Of the various techniques used, intracardiac or intrathoracic injection of a potassium chloride solution was predominant. The experience of each center with multifetal reductions varied between one and six procedures. In this series, the overall complete pregnancy loss was 27% (n = 7). In 73% (n = 19) of women the pregnancy continued to delivery. One fetus died in utero in the second trimester, one child died from a subtentorial hemorrhage perinatally, and one child had a malformation of the right foot and hand. It seems necessary to limit MFR to a few centers in Sweden in order to maintain and increase the experience of the operators involved, and to decrease the fetal loss rate associated with the procedure. However, the ultimate goal is to make these procedures unnecessary when methods of avoiding excessive ovulation are refined and by limiting the number of replaced embryos in IVF-treatment.
Authors:
A Rådestad; T H Bui; K G Nygren
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  73     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-07-15     Completed Date:  1994-07-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  403-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Karolinska sjukhuset, Stockholm, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Abortion, Therapeutic / methods,  statistics & numerical data,  utilization*
Data Collection
Female
Fertilization in Vitro
Humans
Pregnancy
Pregnancy Outcome / epidemiology*
Pregnancy, Multiple*
Questionnaires
Retrospective Studies
Sweden / epidemiology
Utilization Review
Comments/Corrections
Comment In:
Acta Obstet Gynecol Scand. 1996 Jan;75(1):90-1   [PMID:  8561010 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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