Document Detail

Multifactorial risk index for predicting postoperative respiratory failure in men after major noncardiac surgery. The National Veterans Administration Surgical Quality Improvement Program.
MedLine Citation:
PMID:  10903604     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To develop and validate a preoperative risk index for predicting postoperative respiratory failure (PRF).
SUMMARY BACKGROUND DATA: Respiratory failure is an important postoperative complication.
METHOD: Based on a prospective cohort study, cases from 44 Veterans Affairs Medical Centers (n = 81,719) were used to develop the models. Cases from 132 Veterans Affairs Medical Centers (n = 99,390) were used as a validation sample. PRF was defined as mechanical ventilation for more than 48 hours after surgery or reintubation and mechanical ventilation after postoperative extubation. Ventilator-dependent, comatose, do not resuscitate, and female patients were excluded.
RESULTS: PRF developed in 2,746 patients (3.4%). The respiratory failure risk index was developed from a simplified logistic regression model and included abdominal aortic aneurysm repair, thoracic surgery, neurosurgery, upper abdominal surgery, peripheral vascular surgery, neck surgery, emergency surgery, albumin level less than 30 g/L, blood urea nitrogen level more than 30 mg/dL, dependent functional status, chronic obstructive pulmonary disease, and age.
CONCLUSIONS: The respiratory failure risk index is a validated model for identifying patients at risk for developing PRF and may be useful for guiding perioperative respiratory care.
A M Arozullah; J Daley; W G Henderson; S F Khuri
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Annals of surgery     Volume:  232     ISSN:  0003-4932     ISO Abbreviation:  Ann. Surg.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-08-22     Completed Date:  2000-08-22     Revised Date:  2013-06-11    
Medline Journal Info:
Nlm Unique ID:  0372354     Medline TA:  Ann Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  242-53     Citation Subset:  AIM; IM    
Section of General Internal Medicine, University of Illinois College of Medicine, Chicago, Illinois 60612, USA.
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MeSH Terms
Cohort Studies
Middle Aged
Models, Statistical*
Multivariate Analysis
Postoperative Complications / epidemiology*
Respiratory Insufficiency / epidemiology*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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