Document Detail

Multidrug-resistant tuberculosis: case reports study in a central state of Brazil.
MedLine Citation:
PMID:  18553023     Owner:  NLM     Status:  MEDLINE    
Multidrug-resistant tuberculosis (MDR-TB) is an emerging and worrisome health problem that threatens tuberculosis (TB) control worldwide. The clinical management of MDR-TB is a complex issue associated with the use of multiple drugs for a long period, usually accompanied by side effects and high costs. The objective of this work was to relate cases of MDR-TB occurring in Goiás, a central state of Brazil. We related five cases of MDR-TB, three women and two men. All were pulmonary cases. Three were in their second treatment and two in their first treatment. Surgical pulmonary resection was performed in one case. One death occurred. Lack of adherence, gastric intolerance to anti-TB drugs and poor clinical management were the main aspects related to the emergent resistance. A revision of the main clinical aspects of this disease was performed.
João Alves de Araújo-Filho; Arioldo Carvalho Vasconcelos Jr; Eduardo Martins de Sousa; Colombina da Silveira; Patrícia Tavares Pereira de Sousa; Klaus Andrade Severo; Ludmila Ferreira Vieira; André Kipnis; Ana Paula Junqueira-Kipnis
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases     Volume:  12     ISSN:  1678-4391     ISO Abbreviation:  Braz J Infect Dis     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-06-16     Completed Date:  2009-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9812937     Medline TA:  Braz J Infect Dis     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  94-8     Citation Subset:  IM    
Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, GO, Brazil.
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MeSH Terms
Antitubercular Agents / adverse effects,  therapeutic use*
Mycobacterium tuberculosis / drug effects
Tuberculosis, Multidrug-Resistant / drug therapy*,  microbiology,  radiography
Young Adult
Reg. No./Substance:
0/Antitubercular Agents

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