Document Detail


Multidisciplinary approach in cystic hygroma: prenatal diagnosis, outcome, and postnatal follow up.
MedLine Citation:
PMID:  19419502     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The aim of the present study was to determine prenatal follow up and clinical outcome in fetuses born with cystic hygroma. METHODS: A series of 64 cystic hygroma patients, who were diagnosed in the first and the second trimester of pregnancy, was enrolled. Associated structural abnormalities, karyotype analysis and pregnancy outcome were studied. Survivors were followed for their fetal outcome and prognosis. RESULTS: There were 64 new cases of cystic hygroma in 8524 subjects screened (0.75%). Thirty-nine (60.9%) were of non-septated and 25 (39.1%) were of septated cystic hygroma. Chromosomal abnormalities were present in 25 (39.1%). The most common abnormality in non-septated cystic hygroma was trisomy 21 (10, 27.8%), and that in septated cystic hygroma was Turner syndrome (5, 23.8%). Associated structural malformations are common in cystic hygroma and overall survival was poor. Nine of the present infants were live-born and were subsequently followed up. Two had cardiac pathology and died after cardiac operation, two others were diagnosed with axillary cystic hygroma, had an excellent prognosis and responded well to treatment, and another two had cranial findings with mild neurological sequel. Only three cases had, at birth and in the follow-up period, no complications. CONCLUSION: Cystic hygroma is highly correlated with adverse perinatal outcome. Prenatal diagnosis and invasive procedures are vital for counselling with close follow-up after delivery for appropriate medical support. A multidisciplinary approach is strictly recommended in live-born children.
Authors:
Ali Gedikbasi; Kazim Oztarhan; Gulseren Aslan; Oyhan Demirali; Alpaslan Akyol; Akif Sargin; Yavuz Ceylan
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-03-13
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  51     ISSN:  1442-200X     ISO Abbreviation:  Pediatr Int     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-05     Completed Date:  2010-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  670-7     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Istanbul Bakirkoy Maternity and Children's Diseases Hospital, Istanbul, Turkey. alged_1971@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Female
Fetal Diseases / diagnosis,  therapy
Follow-Up Studies
Head and Neck Neoplasms / diagnosis*,  therapy*
Humans
Infant, Newborn
Infant, Newborn, Diseases / diagnosis,  therapy
Interdisciplinary Communication*
Lymphangioma, Cystic / diagnosis*,  therapy*
Male
Patient Care Management / methods*
Pregnancy
Prenatal Diagnosis
Prognosis
Referral and Consultation
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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