Document Detail


Multidetector CT angiography in the assessment of peripheral arterial occlusive disease: accuracy in detecting the severity, number, and length of stenoses.
MedLine Citation:
PMID:  18094974     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose was to evaluate the accuracy of multidetector CT angiography (MD-CTA) in the morphologic assessment of peripheral arterial occlusive disease (PAOD) compared to digital subtraction angiography (DSA). Fifty consecutive patients referred for DSA of the peripheral arteries due to PAOD were prospectively included in this study and underwent 16-row MD-CTA prior to DSA. Maximum intensity projections and multipath curved planar reformations were created with a semi-automated toolbox. Twenty-one vascular segments were defined in each leg and compared to DSA findings with regard to gradation, length, and number of lesions. Mean sensitivity and specificity in the detection of significant stenoses (over 70%) were 100% and 99.5% in the iliac arteries, 97.4% and 99.0% in the femoro-popliteal arteries, and 98.3% and 99.8% in the infrapopliteal arteries, respectively. High kappa values for exact stenoses gradation (0.74-1), lesion length (0.74-1), and number of lesions (0.71-1) were reached by MD-CTA, indicating high agreement with DSA. Non-invasive MD-CTA is an accurate tool for the assessment of all treatment-relevant morphologic information of PAOD (gradation, length, and number of stenoses) compared to DSA.
Authors:
R Schernthaner; A Stadler; F Lomoschitz; M Weber; D Fleischmann; J Lammer; Ch Loewe
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-12-19
Journal Detail:
Title:  European radiology     Volume:  18     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-20     Completed Date:  2008-09-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  665-71     Citation Subset:  IM    
Affiliation:
Department of Radiology, Medical University of Vienna, Vienna, Austria. Ruediger.schernthaner@meduniwien.ac.at
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Angiography / methods*
Angiography, Digital Subtraction
Arterial Occlusive Diseases / pathology,  radiography*
Contrast Media
Female
Humans
Leg / blood supply*
Male
Middle Aged
Peripheral Vascular Diseases / pathology,  radiography*
Radiographic Image Interpretation, Computer-Assisted
Sensitivity and Specificity
Severity of Illness Index
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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