| Multicomponent domino reaction from beta-ketoamides: highly efficient access to original polyfunctionalized 2,6-diazabicyclo[2.2.2]octane cores. | |
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MedLine Citation:
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PMID: 16332052 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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We describe a new multicomponent domino reaction from beta-ketoamides, involved as substrates and as nucleophilic partners. We obtain highly functionalized and original 2,6-diazabicyclo[2.2.2]octane cores (2,6-DABCO) in a five-step one-pot sequence, which is fast, environmentally friendly, operationally simple to manage, and combines step- and atom-economic aspects. |
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Authors:
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Fr?d?ric Li?by-Muller; Thierry Constantieux; Jean Rodriguez |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Chemical Society Volume: 127 ISSN: 0002-7863 ISO Abbreviation: J. Am. Chem. Soc. Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2005-12-07 Completed Date: 2006-02-22 Revised Date: 2008-01-17 |
Medline Journal Info:
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Nlm Unique ID: 7503056 Medline TA: J Am Chem Soc Country: United States |
Other Details:
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Languages: eng Pagination: 17176-7 Citation Subset: - |
Affiliation:
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Universit? Paul C?zanne (Aix-Marseille III), CNRS UMR 6178, SYMBIO, Facult? des Sciences et Techniques, Case D12-13397, Marseille Cedex 20, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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