| Multicentric reticulohistiocytosis: case report with immunohistochemical analysis and literature review. | |
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MedLine Citation:
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PMID: 10765941 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report describes the case of a patient with multicentric reticulohistiocytosis. Immunohistochemical analysis revealed prominent markers of monocyte/macrophage origin, as well as the presence of tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-12; the occurrence of the latter in this disease has not previously been reported. Clinical, laboratory, radiographic, and histologic findings in multicentric reticulohistiocytosis are reviewed. In addition, all published cases of multicentric reticulohistiocytosis which included reports of cytokine and immunohistochemical analysis are reviewed, and evidence for a monocyte/macrophage origin and role in disease pathogenesis is provided. |
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Authors:
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J D Gorman; C Danning; H R Schumacher; J H Klippel; J C Davis |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Arthritis and rheumatism Volume: 43 ISSN: 0004-3591 ISO Abbreviation: Arthritis Rheum. Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-05-18 Completed Date: 2000-05-18 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370605 Medline TA: Arthritis Rheum Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 930-8 Citation Subset: AIM; IM |
Affiliation:
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University of California, San Francisco 94143, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Endothelium, Vascular / pathology Female Histiocytosis, Non-Langerhans-Cell / diagnosis*, pathology, radiography Humans Immunohistochemistry Macrophages / pathology Monocytes / pathology Skin / pathology Staining and Labeling / methods Synovial Membrane / pathology Tumor Necrosis Factor-alpha / metabolism |
| Grant Support | |
ID/Acronym/Agency:
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AR-07304/AR/NIAMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Tumor Necrosis Factor-alpha |
| Comments/Corrections | |
Comment In:
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Arthritis Rheum. 2003 Mar;48(3):864-6
[PMID:
12632456
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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