Document Detail

Multicentric osteolytic lesion of the middle finger of the hand. Case report.
MedLine Citation:
PMID:  22668534     Owner:  NLM     Status:  In-Data-Review    
Giant cell-rich osteolytic lesions may have overlapping clinical, radiologic, and histopathologic features, with an important degree of difficulty of diagnosis and treatment. We report a case of double osteolytic lesion at the middle-finger in a young man without previous history of hand trauma. He underwent en-bloc resection of the bone lesions and reconstruction by graft of hydroxyapatite, resulting in a good morpho-functional result. Histological diagnosis was giant cell reparative granuloma (GCRG), although several features were considered atypical, including the appearance of the giant cells and the areas of the stroma that more closely resembled a giant cell tumor. GCRG is a benign rare intraosseous lesion and the true nature is controversial and unknown. The theories are that it could be a reactive lesion, a developmental anomaly or a benign neoplasm. It appears as an osteolytic lesion that must be considered in the differential diagnosis of other "critical" bone lesions similar in clinical, as well as radiologic and pathological appearance. Further characterization studies are helpful and necessary for the proper management.
G Monacelli; M I Rizzo; C Monarca
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Il Giornale di chirurgia     Volume:  33     ISSN:  0391-9005     ISO Abbreviation:  G Chir     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-06-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9011768     Medline TA:  G Chir     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  136-8     Citation Subset:  IM    
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