Document Detail

Multicenter clinical experience with an atrial lead designed to minimize far-field R-wave sensing.
MedLine Citation:
PMID:  19363053     Owner:  NLM     Status:  MEDLINE    
AIMS: To evaluate a novel atrial lead designed to reduce far-field sensing. METHODS AND RESULTS: Sixty-three patients with standard pacing indications were randomized to receive an OptiSense 1699T (St Jude Medical, USA) or conventional pacing lead in the right atrium. Post-implant follow-up was conducted for all patients at 90 days and for a subset at 360 days. Standard electrical parameters were measured. Thresholds of sensing were determined for far-field ventricular signals. The number of inappropriate mode switches was determined from the stored intracardiac electrogram (IEGM). At 90 days, an IEGM Holter recorded 24 h of IEGM. With atrial sensitivity programmed at 0.3 mV, no far-field sensing occurred in the OptiSense group, but it did occur in 20% and 30% of the control group at 90 and 360 days, respectively. Inappropriate mode switching was observed in 4% of the OptiSense group in contrast to 23% of the control group. The IEGM Holter found no far-field sensing in the OptiSense group, but did find 83 023 far-field events from 22% of control patients. The standard electrical parameters of the OptiSense leads were acceptable. CONCLUSION: The OptiSense lead reduced ventricular far-field sensing in the atrium while maintaining satisfactory pacing and sensing performance, resulting in less inappropriate mode switch.
Jeffrey W H Fung; Johannes Sperzel; Cheuk Man Yu; Joseph Y S Chan; Robert N Gelder; Michael X Yang; Ryan Rooke; Peter Boileau; Gerd Fröhlig
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2009-04-10
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  11     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-29     Completed Date:  2009-06-26     Revised Date:  2009-08-02    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  618-24     Citation Subset:  IM    
Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China.
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MeSH Terms
Aged, 80 and over
Atrial Fibrillation / physiopathology,  therapy*
Electrocardiography, Ambulatory
Equipment Design
Foreign-Body Migration
Heart Atria / physiopathology*
Middle Aged
Pacemaker, Artificial* / adverse effects
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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