Document Detail

Multibranched polyunsaturated and very-long-chain fatty acids of freshwater Israeli sponges.
MedLine Citation:
PMID:  12027746     Owner:  NLM     Status:  MEDLINE    
Very-long-chain and multibranched polyunsaturated fatty acids of three freshwater sponges, Ephydatia syriaca, Nudospongilla sp., and Cortispongilla barroisi, were studied by silver TLC, GC-MS, UV, IR, HRMS, and NMR methods. One hundred and eighty-five conventional fatty acids were identified by GC-MS, out of which five were new multibranched polyunsaturated fatty acids. The freshwater sponges belonging to the family Spongillidae (class Demospongia) were shown to contain novel di-, tri-, and tetramethyl substituted dienoic, tetraenoic, and hexaenoic fatty acids. The compounds gave positive results in a brine shrimp toxicity assay.
Tomás Rezanka; Valery M Dembitsky
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of natural products     Volume:  65     ISSN:  0163-3864     ISO Abbreviation:  J. Nat. Prod.     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-05-24     Completed Date:  2002-08-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7906882     Medline TA:  J Nat Prod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  709-13     Citation Subset:  IM    
Institute of Microbiology, Vídenská 1083, 142 20, Prague, Czech Republic.
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MeSH Terms
Anti-Bacterial Agents / chemistry*,  isolation & purification*
Artemia / drug effects
Bacillus subtilis / drug effects
Chromatography, Thin Layer
Fatty Acids, Unsaturated / chemistry*,  isolation & purification*
Fresh Water
Gas Chromatography-Mass Spectrometry
Molecular Structure
Porifera / chemistry*
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet
Staphylococcus aureus / drug effects
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Fatty Acids, Unsaturated

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