Document Detail

Multi-echo acquisition.
MedLine Citation:
PMID:  22056458     Owner:  NLM     Status:  MEDLINE    
The rapid development of fMRI was paralleled early on by the adaptation of MR spectroscopic imaging (MRSI) methods to quantify water relaxation changes during brain activation. This review describes the evolution of multi-echo acquisition from high-speed MRSI to multi-echo EPI and beyond. It highlights milestones in the development of multi-echo acquisition methods, such as the discovery of considerable gains in fMRI sensitivity when combining echo images, advances in quantification of the BOLD effect using analytical biophysical modeling and interleaved multi-region shimming. The review conveys the insight gained from combining fMRI and MRSI methods and concludes with recent trends in ultra-fast fMRI, which will significantly increase temporal resolution of multi-echo acquisition.
Stefan Posse
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Publication Detail:
Type:  Historical Article; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2011-10-25
Journal Detail:
Title:  NeuroImage     Volume:  62     ISSN:  1095-9572     ISO Abbreviation:  Neuroimage     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-03     Completed Date:  2012-11-19     Revised Date:  2013-08-19    
Medline Journal Info:
Nlm Unique ID:  9215515     Medline TA:  Neuroimage     Country:  United States    
Other Details:
Languages:  eng     Pagination:  665-71     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Department of Neurology, University of New Mexico, Albuquerque, New Mexico 87131, USA.
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MeSH Terms
Brain / physiology
Brain Mapping / history*,  methods
History, 20th Century
History, 21st Century
Image Processing, Computer-Assisted / history,  methods
Magnetic Resonance Imaging / history*,  methods
Magnetic Resonance Spectroscopy / history*,  methods
Grant Support
1R01 EB002618-01/EB/NIBIB NIH HHS; 1R41NS062474-01/NS/NINDS NIH HHS; R01 EB002618-01/EB/NIBIB NIH HHS; R01 EB002618-02/EB/NIBIB NIH HHS; R01 EB002618-03/EB/NIBIB NIH HHS; R01 EB002618-04/EB/NIBIB NIH HHS; R41 NS062474-01/NS/NINDS NIH HHS

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