Document Detail


Multi-center study of a new technique for measuring free thyroxin in serum.
MedLine Citation:
PMID:  2791285     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a multi-center trial we evaluated the accuracy of a new assay kit for free thyroxin (T4), the Behring free T4 RIAgnost, in 1036 subjects: 379 normal subjects, 536 patients with thyroid dysfunction, and 121 subjects with no thyroid dysfunction but with conditions that potentially could interfere with the assay. The kit combines immunoextraction and the use of a modified tracer. Although some limitations remained in using a direct assay method for free T4 in certain nonthyroid conditions, this test was superior to one based on the use of a T4 analog. This kit seems to be very accurate for the diagnosis of untreated thyroid pathologies.
Authors:
M Izembart; M Sala; L Baldet; M Schlumberger; G Deltour
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical chemistry     Volume:  35     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1989-11-17     Completed Date:  1989-11-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2137-9     Citation Subset:  IM    
Affiliation:
Service Central de Radiosiotopes, Groupe Hospitalier Necker-Enfants Malades, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Chemistry, Clinical / standards*
Female
Humans
Male
Middle Aged
Reagent Kits, Diagnostic / standards*
Reference Values
Thyroid Diseases / blood
Thyroid Function Tests
Thyroxine / blood*
Chemical
Reg. No./Substance:
0/Reagent Kits, Diagnostic; 7488-70-2/Thyroxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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