Document Detail


Multi-carbohydrase and phytase supplementation improves growth performance and liver insulin receptor sensitivity in broiler chickens fed diets containing full-fat rapeseed.
MedLine Citation:
PMID:  20709979     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of a combination of carbohydrase and phytase enzymes on growth performance, insulin-like growth factor 1 gene expression, insulin status, and insulin receptor sensitivity in broiler chickens fed wheat-soybean meal diets containing 6% (starter) and 12% (grower-finisher) of full-fat rapeseed (canola type; low glucosinolate, low erucic acid) from 1 to 42 d of age was studied. A total of 510 one-day-old male broiler chickens were randomly assigned to 3 dietary treatments, with 17 pens per treatment and 10 birds per pen. The dietary treatments consisted of a control diet and P- and Ca-deficient diets supplemented with either phytase (500 U/kg) or a combination of phytase and a multi-carbohydrase enzyme (Superzyme OM). The diets were pelleted at 78 degrees C and were fed ad libitum throughout the starter (9 d), grower (18 d), and finisher (15 d) phases of the experiment. Over the entire trial, growth performance of birds fed the phytase-supplemented diet did not differ from birds fed the control diet. The use of phytase in combination with a multicarbohydrase enzyme improved (P = 0.007) the feed conversion ratio from 1.90 to 1.84. Insulin liver receptor sensitivity increased by 9.3 and 12.3% (P = 0.004) for the phytase- and the carbohydrase-phytase-supplemented diets, respectively. There was no effect of phytase alone or carbohydrase and phytase supplementation on total plasma cholesterol, high-density lipoprotein cholesterol, and blood glucose levels. However, low-density lipoprotein cholesterol decreased (P = 0.007) for the phytase-carbohydrase treatment. Gene expression of insulin-like growth factor 1 tended to decrease by 32% (P = 0.083) after phytase-carbohydrase supplementation. The combination of carbohydrase and phytase enzymes may serve as an attractive means of facilitating nutrient availability for digestion and thus enhance the feeding value of wheat-soybean meal-based diets containing full-fat rapeseed. However, the extent to which the effects of enzyme addition on insulin receptors are associated with growth performance of broiler chicken requires further research.
Authors:
D Józefiak; A Ptak; S Kaczmarek; P Mackowiak; M Sassek; B A Slominski
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Poultry science     Volume:  89     ISSN:  0032-5791     ISO Abbreviation:  Poult. Sci.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-16     Completed Date:  2010-10-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401150     Medline TA:  Poult Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1939-46     Citation Subset:  IM    
Affiliation:
Department of Animal Nutrition and Feed Management, University of Life Sciences, 60-637 Poznan, Poland.
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MeSH Terms
Descriptor/Qualifier:
6-Phytase / pharmacology*
Animal Feed
Animal Nutritional Physiological Phenomena
Animals
Brassica rapa / chemistry
Chickens / growth & development*
Diet / veterinary
Dietary Supplements
Gene Expression Regulation, Enzymologic
Glycoside Hydrolases / metabolism*
Insulin-Like Growth Factor I / genetics,  metabolism
Liver / drug effects*
Male
Receptor, Insulin / metabolism*
Seeds / chemistry*
Chemical
Reg. No./Substance:
67763-96-6/Insulin-Like Growth Factor I; EC 2.7.10.1/Receptor, Insulin; EC 3.1.3.26/6-Phytase; EC 3.2.1.-/Glycoside Hydrolases; EC 3.2.1.-/carbohydrase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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