Document Detail


Multi-biomarker approach in wild European bullhead, Cottus sp., exposed to agricultural and urban environmental pressures: Practical recommendations for experimental design.
MedLine Citation:
PMID:  22265682     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In freshwater ecosystems, a large number of chemical substances are able to disturb homeostasis of fish by modulating one or more physiological functions including the immune system. The aim of this study was to assess multi-biomarker responses including immunotoxicity induced by urban and agricultural pressure in European bullheads living in a small French river basin. For this purpose, a set of biochemical, immunological, physiological and histological parameters was measured in wild bullheads from five locations characterized by various environmental pressures. Moreover, to address effects of physiological status and contamination level variation on biomarker responses, fish were sampled during three periods (April, July and October). Results revealed a clear impact of environmental pressure on fish health and particularly on immunological status. An increase of EROD activity was recorded between upstream and downstream sites. Upstream sites were also characterized by neurotoxicological effects. Fish exhibited upstream/downstream variations of immunological status but strong differences were observed according to sampling season. Conversely, regarding biochemical and immunological effects, no significant response of physiological indexes was recorded related to environmental pressures. According to these results, the European bullhead appears as a valuable model fish species to assess adverse effects in wildlife due to urban and agricultural pressures.
Authors:
Sabrina Jolly; Anne Bado-Nilles; Florent Lamand; Cyril Turies; Edith Chadili; Jean-Marc Porcher; Stéphane Betoulle; Wilfried Sanchez
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-20
Journal Detail:
Title:  Chemosphere     Volume:  -     ISSN:  1879-1298     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0320657     Medline TA:  Chemosphere     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Institut National de l'Environnement Industriel et des Risques (INERIS), Unité d'Ecotoxicologie in vitro et in vivo, BP2, 60550 Verneuil-en-Halatte, France; Université de Reims Champagne-Ardenne, Unité de Recherche Vignes et Vins de Champagne - Stress et Environnement EA 2069, Laboratoire Ecologie-Ecotoxicologie, BP 1039, 51687 Reims Cedex 2, France.
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