| Multi-organ failure in a previously healthy 10-year-old boy: streptococcal toxic shock syndrome (STSS) - a rare differential diagnosis. | |
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MedLine Citation:
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PMID: 20556706 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Streptococcal Toxic Shock Syndrome (STSS) is a severe toxin-mediated disease with acute onset. A previously healthy 10-year-old boy presented with abdominal pain, vomiting, diarrhoea and fever for 3 days. He was admitted with signs of an acute abdomen. A treatment with ibuprofen had been started before admission. The child developed a multi-organ failure with persistent hematuria, persistent fever, ascites, pericardial and pleural effusions. Intensive microbial and viral analysis did not result in any relevant finding. Detection by PCR of DNA of the streptococcal super-antigens speM and speL supported the diagnosis of STSS. After an intensive-care treatment of 4 weeks according to international critical-care guidelines the child could be discharged without residuals. |
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Authors:
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B Meedt; B Gharavi; M Imöhl; J-C Becker |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-06-16 |
Journal Detail:
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Title: Klinische Pädiatrie Volume: 222 ISSN: 1439-3824 ISO Abbreviation: Klin Padiatr Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-31 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0326144 Medline TA: Klin Padiatr Country: Germany |
Other Details:
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Languages: eng Pagination: 310-1 Citation Subset: IM |
Copyright Information:
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Georg Thieme Verlag KG Stuttgart, New York. |
Affiliation:
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Marien-Hospital Witten gGmbH, Kinderklinik, Schwerpunkt Neonatologie/Pädiatrische Intensivmedizin, Witten, Germany. Bettina@Meedt.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdomen, Acute
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etiology Bacterial Proteins / genetics Child Diagnosis, Differential Humans Intensive Care Male Multiple Organ Failure / diagnosis*, etiology*, microbiology Polymerase Chain Reaction Shock, Septic / diagnosis*, microbiology Streptococcal Infections / diagnosis*, microbiology Streptococcus pyogenes* / genetics Superantigens / genetics |
| Chemical | |
Reg. No./Substance:
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0/Bacterial Proteins; 0/SpeM protein, Streptococcus pyogenes; 0/Superantigens; 0/speL protein, Streptococcus pyogenes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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