Document Detail

Muir-torre syndrome: a case report.
MedLine Citation:
PMID:  20729952     Owner:  NLM     Status:  In-Data-Review    
Muir-Torre syndrome is an autosomal dominant genodermatosis associated with sebaceous neoplasms and visceral malignancies. Characteristic sebaceous neoplasms include sebaceous adenoma, sebaceous carcinoma, sebaceoma, and keratoacanthoma with sebaceous differentiation. The most common visceral malignancies are colorectal and genitourinary tumors. Investigations into the molecular genetics of Muir-Torre Syndrome have revealed an association with germ-line mutations in hMSH2 and hMLH1 genes. The clinical and histological features of a patient with Muir-Torre syndrome who had two sebaceous adenomas, multiple basal cell carcinomas, and frontal bossing in association with colon cancer are presented in this report.
Heather J Higgins; Melissa Voutsalath; Jean M Holland
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of clinical and aesthetic dermatology     Volume:  2     ISSN:  1941-2789     ISO Abbreviation:  J Clin Aesthet Dermatol     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2010-08-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101518173     Medline TA:  J Clin Aesthet Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  30-2     Citation Subset:  -    
Oakwood Southshore Medical Center, Trenton, Michigan.
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