| The Muir-Torre syndrome: a disease of sebaceous and colonic neoplasms. | |
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MedLine Citation:
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PMID: 2917677 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Muir-Torre syndrome of sebaceous neoplasms of the skin, with or without keratoacanthomas, and multiple low-grade visceral malignancies with prolonged survival is a rare disorder. Colonic polyps are frequently present, and the syndrome appears to be familial. We report 2 unrelated patients with the Muir-Torre syndrome. Each case exhibited sebaceous adenomas. Gastrointestinal findings included colonic adenocarcinomas and a tubulovillous adenoma. Although an unusual disease, the Muir-Torre syndrome requires recognition because these patients are at risk for multiple primary malignancies and may have family members also at risk. |
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Authors:
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R A Schwartz; D J Goldberg; F Mahmood; R L DeJager; W C Lambert; A Z Najem; P J Cohen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Dermatologica Volume: 178 ISSN: 0011-9075 ISO Abbreviation: Dermatologica Publication Date: 1989 |
Date Detail:
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Created Date: 1989-03-29 Completed Date: 1989-03-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0211607 Medline TA: Dermatologica Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 23-8 Citation Subset: IM |
Affiliation:
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Department of Dermatology, New Jersey Medical School, Newark. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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genetics* Adenoma / genetics*, pathology Adult Chromosome Aberrations / genetics Chromosome Disorders Colorectal Neoplasms, Hereditary Nonpolyposis / genetics* Facial Neoplasms / genetics Genes, Dominant Humans Male Middle Aged Neoplasms, Multiple Primary / genetics*, pathology Sebaceous Gland Neoplasms / genetics*, pathology Sebaceous Glands / pathology Syndrome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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