Document Detail

Mugineic acid: non-selective enhancement of excitatory amino acid actions on rat central neurones.
MedLine Citation:
PMID:  3431667     Owner:  NLM     Status:  MEDLINE    
The effects of mugineic acid upon excitations induced by quisqualic acid (quis), N-methyl-D-aspartic acid (NMDA) and kainic acid (kain) on rat central neurones were examined in vivo through microiontophoretic drug administration in anaesthetized rats. Mugineic acid usually caused a non-selective enhancement of drug-induced excitations, occasionally producing direct excitation itself or increasing the rate of spontaneous discharge. Mugineic acid-induced effects were not blocked by the NMDA selective antagonist, 2-amino-5-phosphonovaleric acid (AP5).
T Kaneko; T P Hicks; L Bauce
Related Documents :
7953687 - Immunocytochemical localization of the quinolinic acid synthesizing enzyme, 3-hydroxyan...
2549447 - Differential effects of (d)- and (l)-homocysteic acid on the membrane potential of cat ...
3531927 - Ketamine selectively suppresses synchronized afterdischarges in immature hippocampus.
7666677 - The effect of quinolinic acid administered during pregnancy on the hippocampal formatio...
4065407 - A comparison of the lipid classes and essential fatty acid content of rat plasma lipopr...
11432467 - Method to produce 9(s)-hydroperoxides of linoleic and linolenic acids by maize lipoxyge...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuropharmacology     Volume:  26     ISSN:  0028-3908     ISO Abbreviation:  Neuropharmacology     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1988-03-09     Completed Date:  1988-03-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0236217     Medline TA:  Neuropharmacology     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1649-52     Citation Subset:  IM    
Department of Medical Physiology, Faculty of Medicine, University of Calgary, Alberta, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amino Acids / pharmacology*
Azetidinecarboxylic Acid / analogs & derivatives,  pharmacology*
Azetines / pharmacology*
Evoked Potentials / drug effects
Neurons / drug effects*,  physiology
Plants / analysis
Stimulation, Chemical
Reg. No./Substance:
0/Amino Acids; 0/Azetines; 2517-04-6/Azetidinecarboxylic Acid; 69199-37-7/mugineic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Localization of ARG-vasopressin-like material in central neurones and mechanism of action of ARG-vas...
Next Document:  In vivo electrochemical determination of extracellular dopamine in the caudate of freely-moving rats...