Document Detail

Mucosal IgA response to repeated wingate tests in females.
MedLine Citation:
PMID:  11281615     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to examine the effect of repeated bouts of brief, intermittent, maximal effort exercise on the concentration of secretory IgA (S-IgA) and incidence of upper respiratory tract infection (URTI) in females. Twenty-six non-smoking, active, adult females participated in this study. The exercise intervention consisted of three consecutive, all-out 30-second Wingate leg cycling tests (0.075 kg/kg body mass), which were separated by three minutes of recovery. Unstimulated saliva was collected prior to (PRE) and five minutes after completion (POST) of the exercise testing protocol. IgA, protein and osmolality were measured, and secretory IgA (SIgA), IgA:Protein, and IgA: Osmolality were calculated. In addition, subjects completed standard logs indicating signs and symptoms of upper respiratory tract infection (URTI) for three weeks following the test. Saliva flow rates (478.5 +/- 50; 345.4 +/- 50 microl/min), S-IgA (55.8 +/- 4.7; 35.4 +/- 3.6 microg/min), and IgA: Protein ratio (30.7 +/- 3.0; 17.5 +/- 1.8 microg IgA/mg protein) were significantly lower POST compared to PRE (P < 0.05). No significant differences were observed for raw IgA, protein, osmolality, and IgA: osmolality. The results of this study show that brief, intermittent, maximal effort exercise results in an acute decrease in S-IgA in healthy adult females in less than eight minutes. However, this exercise induced transient decrease did not appear to be associated with an increase in clinical symptoms of URTI in the weeks following the exercise test intervention.
M M Fahlman; H J Engels; A L Morgan; I Kolokouri
Related Documents :
2079845 - Effects of age on heart rate response during a strenuous match of tennis.
23686775 - Moderate-intensity single exercise session does not induce renal damage.
17852695 - Changes in jump performance and muscle activity following soccer-specific exercise.
11375875 - The acute phase response and exercise: court and field sports.
19346625 - Effects of a 4-week exercise program on balance using elastic tubing as a perturbation ...
19997015 - Massage impairs postexercise muscle blood flow and "lactic acid" removal.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of sports medicine     Volume:  22     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-04-02     Completed Date:  2001-05-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  127-31     Citation Subset:  IM    
Wayne State University, Detroit, MI 48202, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Exercise / physiology*
Exercise Test
Immunoglobulin A / analysis*
Mucous Membrane / immunology
Respiratory Tract Infections / etiology,  immunology*
Reg. No./Substance:
0/Immunoglobulin A
Erratum In:
Int J Sports Med 2001 May;22(4):284

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Attenuation of increase in circulating cortisol and enhancement of the acute phase protein response ...
Next Document:  The effect of moderate aerobic exercise and relaxation on secretory immunoglobulin A.