| Mucosa-associated lymphoid tissue in individuals with AIDS. | |
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MedLine Citation:
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PMID: 21739004 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To characterize fibrosis and immunoglobulin production in vestibular fold lymphoid tissues of AIDS patients with or with no infection and malnutrition. MATERIALS AND METHODS: A retrospective study of 71 adult vestibular fold autopsy specimens. The morphological analysis was done using the picrosirius staining method. Immunohistochemical methods consisted of anti-IgA, anti IgG, and anti IgM antibodies. RESULTS: Fibrosis was less intense in AIDS patients compared to subjects without AIDS; the same applied to patients with infection or malnutrition. IgA and IgG titers were higher in AIDS patients; IgM titers were higher in cases with infection. CONCLUSION: This study helps understand variations in lymphoid follicle components of AIDS patients; it also shows the influence of architectural changes and the effect of associated respiratory infection and malnutrition on lymphoid follicle function. |
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Authors:
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Janainna Grazielle Pacheco Olegario; Renata Calciolari Rossi E Silva; Vicente de Paula Antunes Teixeira; Eumênia Costa da Cunha Castro; Rosana Rosa Miranda Corrêa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Brazilian journal of otorhinolaryngology Volume: 77 ISSN: 1808-8686 ISO Abbreviation: Braz J Otorhinolaryngol Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-07-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101207337 Medline TA: Braz J Otorhinolaryngol Country: Brazil |
Other Details:
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Languages: eng; por Pagination: 308-14 Citation Subset: IM |
Affiliation:
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Triangulo Mineiro Federal University. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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