Document Detail

Mucormycotic pseudoaneurysm of the common carotid artery with tracheal involvement.
MedLine Citation:
PMID:  18855846     Owner:  NLM     Status:  MEDLINE    
Mucormycosis is an emerging and fatal fungal infection. A high index of suspicion and the knowledge of its potential manifestations are essential for early diagnosis. We describe a patient with acute lymphoblastic leukaemia (L2 subtype) who developed a neck mass following a course of induction chemotherapy. Doppler ultrasonography and angiography of the neck revealed a pseudoaneurysm of the right common carotid artery. The patient then developed haemoptysis. Surgical exploration revealed a necrotic right common carotid artery with anteromedial pseudoaneurysm and adjacent tracheal wall perforation. Local debridement and tracheal repair were performed. Nonseptate hypheal invasion (mucormycosis) was found on the microscopic examination of the excised arterial wall. A subsequent recurrence of pseudoaneurysm was treated with local surgical debridement and intravenous amphotericin B (Fungizone) administration. Although rare, clinicians should be aware of these possible presenting features of mucormycosis as early diagnosis and treatment may potentially improve the survival.
S Hashemzadeh; R S Tubbs; M B A Fakhree; M M Shoja
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Publication Detail:
Type:  Case Reports; Letter    
Journal Detail:
Title:  Mycoses     Volume:  51     ISSN:  1439-0507     ISO Abbreviation:  Mycoses     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-10-15     Completed Date:  2008-11-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8805008     Medline TA:  Mycoses     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  347-51     Citation Subset:  IM    
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MeSH Terms
Amphotericin B / therapeutic use
Aneurysm, False / microbiology*
Antifungal Agents / therapeutic use
Carotid Artery, Common / microbiology*,  radiography,  surgery,  ultrasonography
Mucorales / cytology
Mucormycosis / complications*,  diagnosis*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
Tracheal Diseases / etiology,  surgery
Reg. No./Substance:
0/Antifungal Agents; 1397-89-3/Amphotericin B

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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