Document Detail


Mucoepidermoid carcinoma of salivary glands in the pediatric age group: 18 clinical cases, including 11 second malignant neoplasms.
MedLine Citation:
PMID:  16783829     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Salivary gland tumors represent 1% of head and neck tumors, with only 5% of these occurring in patients younger than 20 years. Mucoepidermoid carcinoma (MEC) is one of the most frequent salivary gland cancers among adults and children. METHODS: This survey was conducted among 34 French pediatric oncology departments. From 1980 to 2000, 18 cases were reported. RESULTS: Treatment included surgery or radiotherapy, or both. The 5-year survival rate was 93.7%. Eleven patients had been previously treated by radiotherapy and/or chemotherapy for a first malignant tumor, specifically, lymphoid leukemia (n = 4), lymphoma (n = 3), brain tumor (n = 2), sarcoma (n = 1), and retinoblastoma (n = 1). CONCLUSIONS: MEC is very rare in the pediatric age group. Treatment involves surgical removal of the tumor plus radiotherapy, according to histologic staging. MEC has a good prognosis in young patients. The survival rate does not differ in the subgroup of patients with MEC as a secondary tumor.
Authors:
Pierre Olivier Védrine; Laurent Coffinet; Stéphane Temam; Karine Montagne; Michel Lapeyre; Odile Oberlin; Daniel Orbach; Claude Simon; Danièle Sommelet
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Head & neck     Volume:  28     ISSN:  1043-3074     ISO Abbreviation:  Head Neck     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-28     Completed Date:  2006-12-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  United States    
Other Details:
Languages:  eng     Pagination:  827-33     Citation Subset:  IM    
Copyright Information:
(c) 2006 Wiley Periodicals, Inc.
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Hôpital Les Broussailles, Cannes, France. vedrine@yahoo.fr
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Carcinoma, Mucoepidermoid / pathology*,  secondary,  therapy
Child
Child, Preschool
Female
Humans
Lymphoma / pathology
Male
Neoplasms, Neuroepithelial / pathology
Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
Rhabdomyosarcoma / pathology
Salivary Gland Neoplasms / pathology*,  secondary,  therapy

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