Document Detail


Mucocutaneous candidiasis.
MedLine Citation:
PMID:  14626505     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mucocutaneous infection with Candida in neonates ranges from such common conditions as thrush and diaper dermatitis to serious diseases with potential for systemic involvement, including congenital candidiasis and invasive fungal dermatitis. In premature infants, seemingly benign mucocutaneous involvement may precede systemic infection and thus warrants thoughtful attention. Skin involvement also may be seen as an expression of systemic disease. The physical appearance of these lesions is often characteristic, allowing easy diagnosis. The patients at risk differ by gestational age and postnatal age at presentation. Systemic candidiasis and invasive fungal dermatitis typically occur in premature infants, particularly those with extremely low birth weight (< or = 1,000 g), whereas thrush and diaper dermatitis may occur in infants of any gestational age or birth weight. Congenital candidiasis presents at birth, while invasive fungal dermatitis typically occurs within the first 2 weeks of life, and thrush, diaper dermatitis, and systemic candidiasis may occur at any time in infancy. Controversy exists concerning optimal therapy of mucocutaneous candidiasis.
Authors:
Judith L Rowen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in perinatology     Volume:  27     ISSN:  0146-0005     ISO Abbreviation:  Semin. Perinatol.     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-11-19     Completed Date:  2004-03-04     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7801132     Medline TA:  Semin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  406-13     Citation Subset:  IM    
Affiliation:
Division of Infectious Diseases, Department of Pediatrics, University of Texas Medical Branch at Galveston, Galveston, TX 77555-0371, USA. jrowen@utmb.edu
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MeSH Terms
Descriptor/Qualifier:
Candidiasis, Chronic Mucocutaneous / complications,  congenital,  diagnosis*,  drug therapy*
Diaper Rash / complications
Humans
Infant, Newborn
Infant, Very Low Birth Weight
Intestinal Perforation / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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