| Mucociliary clearance in cystic fibrosis. | |
| | |
MedLine Citation:
|
PMID: 11921459 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Abnormal mucociliary clearance (MCC) is one of the central hypotheses for the development of lung disease in patients with cystic fibrosis (CF). However, attempts to demonstrate this decrease of MCC in vivo have proved to be somewhat less definitive, with the evidence barely favoring impaired clearance. Any apparent disparities are most likely due to the variety of methodologies used by different laboratories to measure MCC. The limitations of the various methodologies are examined in this review, in an attempt to better facilitate comparison of results. A number of physical and pharmacological therapies have been developed to promote mucus clearance from the CF airway. A summary of the results of interventional studies utilizing the measurement of MCC as an outcome measure is presented. |
| | |
Authors:
|
Michael Robinson; Peter T B Bye |
Related Documents
:
|
13991999 - Pulmonary changes seen in lung purpura and some of the other collagen diseases. 3480819 - Pulmonary surfactant and chronic lung disease. 3813209 - Sarcoidlike lung granulomatosis induced by aluminum dusts. 12556929 - Urinary tract infection with trichomonas vaginalis in a premature newborn infant and th... 10161099 - Clinical efficacy and safety of turbuhaler as compared to pressurized mdis-beta 2-agoni... 15612029 - Correction of the cf defect by curcumin: hypes and disappointments. 6724249 - Alterations in levels of apolipoprotein c-iii and c-ii/c-iii ratios in patients with li... 15702409 - Screening for menkes disease using the urine hva/vma ratio. 11205149 - Dementia with lewy bodies: prevalence, clinical spectrum and natural history. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Pediatric pulmonology Volume: 33 ISSN: 8755-6863 ISO Abbreviation: Pediatr. Pulmonol. Publication Date: 2002 Apr |
Date Detail:
|
Created Date: 2002-03-28 Completed Date: 2002-04-26 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8510590 Medline TA: Pediatr Pulmonol Country: United States |
Other Details:
|
Languages: eng Pagination: 293-306 Citation Subset: IM |
Copyright Information:
|
Copyright 2002 Wiley-Liss, Inc. |
Affiliation:
|
Cystic Fibrosis Centre (E11S), Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales 2050, Australia. mr@mail.med.usyd.edu.au |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Clinical Trials as Topic Cough / physiopathology Cystic Fibrosis / etiology, physiopathology*, radionuclide imaging Disease Models, Animal Humans Mice Mucociliary Clearance / physiology* Nasal Mucosa / physiology Outcome Assessment (Health Care) |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Exhaled nitric oxide concentrations: online versus offline values in healthy children.
Next Document: Irreversible airway obstruction in childhood asthma? A clinician's viewpoint.