Document Detail


The Mucin degrader Akkermansia muciniphila is an abundant resident of the human intestinal tract.
MedLine Citation:
PMID:  18083887     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 16S rRNA-targeted probe, MUC-1437, was designed and validated in order to determine the presence and numbers of cells of Akkermansia muciniphila, a mucin degrader, in the human intestinal tract. As determined by fluorescent in situ hybridization, A. muciniphila accounted more than 1% of the total fecal cells and was shown to be a common bacterial component of the human intestinal tract.
Authors:
Muriel Derrien; M Carmen Collado; Kaouther Ben-Amor; Seppo Salminen; Willem M de Vos
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-12-14
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  74     ISSN:  1098-5336     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-26     Completed Date:  2008-03-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1646-8     Citation Subset:  IM    
Affiliation:
Laboratory of Microbiology, Dreijenplein 10, 6703 HB Wageningen, The Netherlands. muriel.derrien@wur.nl
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MeSH Terms
Descriptor/Qualifier:
Bacteria / genetics,  metabolism*
Computational Biology
DNA Primers / genetics
Feces / microbiology*
Flow Cytometry
Gastric Mucins / metabolism*
Humans
In Situ Hybridization, Fluorescence
Intestines / microbiology*
Oligonucleotide Probes / genetics
Phylogeny*
RNA, Ribosomal, 16S / genetics
Chemical
Reg. No./Substance:
0/DNA Primers; 0/Gastric Mucins; 0/Oligonucleotide Probes; 0/RNA, Ribosomal, 16S
Comments/Corrections

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