| Moyamoya syndrome after prophylactic cranial irradiation for acute lymphocytic leukemia. | |
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MedLine Citation:
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PMID: 14512691 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 9-year-old boy presented with an episode of syncope, and MR imaging revealed bilateral internal carotid artery stenosis with moyamoya vessel formation. He had had prophylactic cranial irradiation at a total dose of 24 Gy for the treatment of acute lymphocytic leukemia at the age of 4. Following this, he was in a complete state of remission for 6 years. During an observation period of a year after the onset of syncope, MR imaging showed development of multiple ischemic lesions in both hemispheres. He developed a transient ischemic attack of mild motor weakness in his arm and an indirect anastomosis was performed on the severely affected side at the age of 10. Radiation-induced vasculopathies are known to be associated with primary diseases of intracranial tumors, but the frequency is unclear. Ours is the third case in whom prophylactic cranial irradiation for a hematological disorder might have induced cerebral vasculopathies. |
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Authors:
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Takeshi Kondoh; Akitsugu Morishita; Masahito Kamei; Yusuke Okamura; Masahiro Tamaki; Eiji Kohmura |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric neurosurgery Volume: 39 ISSN: 1016-2291 ISO Abbreviation: Pediatr Neurosurg Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-09-26 Completed Date: 2003-11-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9114967 Medline TA: Pediatr Neurosurg Country: Switzerland |
Other Details:
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Languages: eng Pagination: 264-9 Citation Subset: IM |
Copyright Information:
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Copyright 2003 S. Karger AG, Basel |
Affiliation:
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Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan. tkondo@med.kobe-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain Ischemia
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etiology Child Cranial Irradiation / adverse effects* Humans Magnetic Resonance Imaging Male Moyamoya Disease / etiology* Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications, radiotherapy* Radiation Injuries / pathology* Syncope / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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