Document Detail

Moving dipole analysis of normal and abnormal ventricular activation by magnetocardiography.
MedLine Citation:
PMID:  11953909     Owner:  NLM     Status:  MEDLINE    
The current source during ventricular excitation of the in situ heart has not been well characterized. We analyzed current dipoles of ventricular excitation by magnetocardiography (MCG) in 16 healthy subjects and 10 patients with the Wolff-Parkinson-White syndrome or premature ventricular contraction. Single current dipoles were estimated by MCG with the spatial position, direction, and strength in the initial 40 ms of QRS (moving dipole analysis). In 12 of the 16 healthy subjects, the origin of current dipoles moved consecutively from the initial position with the increase in the peak strength at 30 ms of QRS. In the other 4 healthy subjects, dipoles moved discontinuously jumping to the right-anterior thorax at 17.8 ms (mean). In abnormal ventricular excitation, the dipoles remained in the initial position with little movement, smaller strength of dipole than that of normal with a delayed peak time. The moving dipole analysis can be applied to determine spatial distribution of normal and abnormal excitation sources at the initial phase of ventricular depolarization in the in situ heart.
Yasunaga Hiyoshi; Harumizu Sakurada; Naomi Izumida; Seiko Kawano; Tohru Sawanobori; Masayasu Hiraoka
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  35     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-04-15     Completed Date:  2002-05-22     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  105-13     Citation Subset:  IM    
Department of Internal Medicine, Tokyo Metropolitan Ebara Hospital, Japan.
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MeSH Terms
Electromagnetic Fields
Heart Ventricles / physiopathology*
Image Enhancement
Magnetic Resonance Imaging
Middle Aged
Statistics as Topic
Vectorcardiography / methods*
Wolff-Parkinson-White Syndrome / diagnosis*,  physiopathology*

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