Document Detail

Movement of cell-associated matrix during contact competition of cells in mixed cultures.
MedLine Citation:
PMID:  8348116     Owner:  NLM     Status:  MEDLINE    
Co-cultured contacting heterotypic cell groups compete with one another for the attachment to the substratum. In the course of this competition one cell group can progressively push another from the substratum. Alterations to the distribution of cell-associated matrix structures in the course of contact competition were examined by immunomorphological methods in the paired cultures of two epithelial lines and those of fibroblasts and epithelia. It was found that matrix structures formed by the retreating cells withdrew from the substratum simultaneously with the cells. These results show that two forms of matrix structures should be distinguished: the usually immovable matrix upon which the cells crawl and the movable matrix that the cells carry with them when they move.
L V Domnina; E K Fetisova; J M Vasiliev
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell biology international     Volume:  17     ISSN:  1065-6995     ISO Abbreviation:  Cell Biol. Int.     Publication Date:  1993 Jun 
Date Detail:
Created Date:  1993-09-16     Completed Date:  1993-09-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9307129     Medline TA:  Cell Biol Int     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  573-8     Citation Subset:  IM    
A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Russia.
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MeSH Terms
Cell Communication*
Cell Line
Cells, Cultured
Epithelial Cells
Epithelium / physiology
Fibroblasts / cytology,  physiology
Fibronectins / analysis
Fluorescent Antibody Technique
Reg. No./Substance:

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