| Mouse oviduct development. | |
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MedLine Citation:
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PMID: 22918811 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The oviduct, or Fallopian tube in humans, transports oocytes and sperm, serves as the site of fertilization, and supports early embryonic development. The oviduct is essential for fertility. In the mouse, the oviduct is a coiled, complex structure that develops from the simple embryonic Müllerian duct. The oviduct consists of four segments, including the infundibulum, ampulla, isthmus, and uterotubal junction. Additionally, the mouse oviduct forms coils, develops longitudinal folds, and undergoes both mesenchymal and epithelial differentiation. Oviduct development and differentiation occurs perinatally. Several signaling pathways have been found to be involved in oviduct formation, such as Wnt, Tgfβ, microRNA processing, as well as others. Overall, the process of oviduct development is poorly understood and can be utilized to further knowledge of epithelial-mesenchymal interactions, regulation of coiling, characteristics of pseudostratified epithelia, and smooth muscle differentiation. |
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Authors:
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C Allison Stewart; Richard R Behringer |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Results and problems in cell differentiation Volume: 55 ISSN: 0080-1844 ISO Abbreviation: Results Probl Cell Differ Publication Date: 2012 |
Date Detail:
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Created Date: 2012-08-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0173555 Medline TA: Results Probl Cell Differ Country: Germany |
Other Details:
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Languages: eng Pagination: 247-62 Citation Subset: IM |
Affiliation:
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Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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