| Mouse models of atherosclerosis. | |
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MedLine Citation:
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PMID: 22314832 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Genetically altered mice carrying mutations of genes encoding crucial components of the immune system and lipid metabolism have been widely used to study the role of immune responses and inflammation in atherosclerosis. These mice are often fed a diet, with a high content of cholesterol and saturated fat in order to induce hypercholesterolemia and arterial lesions. We review the different mouse models of atherosclerosis, type of diets, and techniques to measure lipid deposition and lesion size in the arterial walls. Moreover, the methods used to determine the presence of the immune cells in atherosclerotic lesions are also described here. Curr. Protoc. Immunol. 96:15.24.1-15.24.23. © 2012 by John Wiley & Sons, Inc. |
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Authors:
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E Maganto-Garcia; M Tarrio; A H Lichtman |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current protocols in immunology / edited by John E. Coligan ... [et al.] Volume: Chapter 15 ISSN: 1934-368X ISO Abbreviation: Curr Protoc Immunol Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-02-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9101651 Medline TA: Curr Protoc Immunol Country: United States |
Other Details:
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Languages: eng Pagination: Unit15.24 Citation Subset: IM |
Affiliation:
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Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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